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324M-1 Sigma-Aldrich

PSA (ER-PR8) Mouse Monoclonal Antibody



Related Categories Alphabetical Index, Anatomic Pathology, Antibodies, Cell Marque Antibodies, Genitourinary (GU) Pathology,
Quality Level   GMP-IVD
biological source   mouse
antibody form   culture supernatant
antibody product type   primary antibodies
clone   ER-PR8, monoclonal
description   For In Vitro Diagnostic Use in Select Regions (See Chart)
form   buffered aqueous solution
species reactivity   human
packaging   vial of 0.1 mL concentrate (324M-14)
  vial of 0.5 mL concentrate (324M-15)
  bottle of 1.0 mL predilute (324M-17)
  vial of 1.0 mL concentrate (324M-16)
  bottle of 7.0 mL predilute (324M-18)
mfr. no.   Cell Marque
concentration   0.01-1 μg/mL (predilute)
  0.25-25 μg/mL (concentrate)
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
isotype   IgG1κ
conjugate   unconjugated
control   prostate
shipped in   wet ice
storage temp.   2-8°C
visualization   cytoplasmic


General description

Prostate-Specific Antigen (PSA) is a 33 kDa protein primarily produced by the prostatic epithelium and the epithelial lining of the periurethral glands . PSA is strongly expressed in both normal and neoplastic prostatic tissue. Although PSA can be considered prostate-specific, PSA and/or PSA gene expression has been detected at low levels in some extra-prostatic tissues such as normal breast tissue, breast tumors, endometrium, adrenal neoplasms and renal cell carcinomas. Anti-PSA is most useful in determining the prostatic origin of carcinomas in non-prostate tissues (metastatic disease) using IHC techniques. This product is best used in conjunction with a panel of antibodies as, up to 27% of prostate carcinoma cases (predominantly poorly differentiated carcinomas) can be negative for this marker.


PSA Positive Control Slides, Product No. 324S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Preparation Note

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Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

NONH for all modes of transport


Certificate of Analysis

Protocols & Articles


Antibody Basics

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324S PSA Positive Control Slides, immunohistochemistry (formalin-fixed, paraffin-embedded sections) 

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