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329M-9 Sigma-Aldrich

Renal Cell Carcinoma (PN-15) Mouse Monoclonal Antibody

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Properties

Related Categories Alphabetical Index, Anatomic Pathology, Antibodies, Cell Marque Antibodies, Primary Antibodies,
Quality Level   GMP-IVD
biological source   mouse
antibody form   culture supernatant
antibody product type   primary antibodies
clone   PN-15, monoclonal
description   For In Vitro Diagnostic Use in Select Regions (See Chart)
form   buffered aqueous solution
species reactivity   human
packaging   vial of 0.1 mL concentrate (329M-94)
  vial of 0.5 mL concentrate (329M-95)
  bottle of 1.0 mL predilute (329M-97)
  vial of 1.0 mL concentrate (329M-96)
  bottle of 7.0 mL predilute (329M-98)
mfr. no.   Cell Marque
concentration   15.0-35.0 μg/mL (predilute)
  750-1750 μg/mL (concentrate)
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
isotype   IgG1κ
conjugate   unconjugated
control   renal cell carcinoma
shipped in   wet ice
storage temp.   2-8°C
visualization   cytoplasmic, membranous

Description

General description

Anti-renal cell carcinoma (RCC) recognizes a 200 kD glycoprotein localized in the brush border of the proximal renal tubule. This antibody immunoreacts with approximately 90% of primary renal cell carcinomas and approximately 85% of metastatic renal cell carcinomas. Other tumors that may react with this antibody are parathyroid adenoma and an occasional breast carcinoma. Nephroblastoma, oncocytoma, mesoblasticnephroma, transitional cell carcinoma, and angiomyolipoma are not labeled with this antibody.

Linkage

Renal Cell Carcinoma Positive Control Slides, Product No. 329S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Preparation Note

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Quality


IVD

IVD

IVD

RUO

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

References

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Description

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329S Renal Cell Carcinoma Positive Control Slides, immunohistochemistry (formalin-fixed, paraffin-embedded sections) 

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