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40584 Sigma-Aldrich

Amentoflavone

≥99.0% (HPLC)

Synonym: Didemethyl-ginkgetin, I3′,II8-Biapigenin, Tridemethylsciadopitysin

  • CAS Number 1617-53-4

  • Empirical Formula (Hill Notation) C30H18O10

  • Molecular Weight 538.46

  •  Beilstein/REAXYS Number 380244

  •  MDL number MFCD00017470

  •  PubChem Substance ID 57650005

  •  NACRES NA.47

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Properties

Related Categories Cell Biology, Ginkgo biloba, Hematology and Histology, Hypericum perforatum (St John′s wort), Natural Dyes,
Quality Level   100
assay   ≥99.0% (HPLC)
storage temp.   2-8°C
SMILES string   Oc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)c(c3O2)-c4cc(ccc4O)C5=CC(=O)c6c(O)cc(O)cc6O5
InChI   1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-36H
InChI key   YUSWMAULDXZHPY-UHFFFAOYSA-N
Gene Information   human ... GABRA1(2554)

Description

Biochem/physiol Actions

Biflavonoid with anti-inflammatory, anti-viral and cancer chemopreventive activity. It inhibits vascularization of tumors by blocking the activity of angiogenic VEGFs. Blocks the induction of COX-2 and up-regulates PPAR-γ. It is a negative modulator of the GABAA receptor at the benzodiazepine binding site.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.1 During the oxi...
Biofiles Volume 2 Article 2
Keywords: Adhesion, Anti-inflammatory agents, Applications, Cancer, Cardiovascular, Catalysis, Diabetes, Diseases, Gene expression, Metabolism, Neurodegenerative Diseases, Peroxidations, Phosphorylations, Prebiotics, Probiotics, Reductions, Transcription, Transduction, Vitamins

Peer-Reviewed Papers
15

References

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