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41111 Sigma-Aldrich

Ajmalicine

≥98.0% (HPLC)

Synonym: δ-Yohimbine, Py-Tetrahydroserpentine, Raubasine

  • CAS Number 483-04-5

  • Empirical Formula (Hill Notation) C21H24N2O3

  • Molecular Weight 352.43

  •  Beilstein/REAXYS Number 97268

  •  EC Number 207-589-5

  •  NACRES NA.25

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Properties

Related Categories Cell Biology, Metabolic Pathways, Metabolomics, Terpenoid Metabolism, Terpenoids More...
Quality Level   100
assay   ≥98.0% (HPLC)
optical activity   [α]/D -65±3°, c = 1 in chloroform
mp   ~258 °C (dec.)
storage temp.   2-8°C

Description

Application

Ajmalicine (δ-Yohimbine, Py-Tetrahydroserpentine, Raubasine) is an alkaloid used to study its effects as an antagonist of adrenergic and nicotinic receptors.

Biochem/physiol Actions

Metabolite in the indole alkaloid biosynthesis (serpentine production); found naturally in various plants such as Rauwolfia spp., Catharanthus roseus, and Mitragyna speciosa. It shows antimicrobial activity, and is used as an anti-hypertensive and sedative.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
AX7875000

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of Yohimbe Alkaloids on Ascentis® Express F5, HILIC Mode

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Yohimbe Alkaloids on Ascentis® Express F5, HILIC Mode
Keywords: Chromatography, High performance liquid chromatography, Vitamins

Peer-Reviewed Papers
15

References

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