• USA Home
  • 42965 - Tramadol hydrochloride

EMAIL THIS PAGE TO A FRIEND
42965 Sigma-Aldrich

Tramadol hydrochloride

≥99.0% (HPLC)

Synonym: (±)-cis-2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride, Tramadol HCl

Purchase

Properties

Quality Level   200
assay   ≥99.0% (HPLC)
drug control   USDEA Schedule IV
mp   178-181 °C
SMILES string   Cl.COc1cccc(c1)[C@@]2(O)CCCC[C@@H]2CN(C)C
InChI   1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/m1./s1
InChI key   PPKXEPBICJTCRU-XMZRARIVSA-N

Description

Application

Tramadol hydrochloride has been used to study the tramadol biosynthesis route in plants.

Biochem/physiol Actions

Tramadol hydrochloride (HCl) inhibits the reuptake of norepinephrine and serotonin in μ-opioid receptors in rat models in vitro.

Opioid analgesic; P450 substrate.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN2811 - class 6.1 - PG 3 - MP - EHS - Toxic solids, organic, n.o.s., HI: all
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Articles

HPLC Analysis of Tramadol Enantiomers on Astec® CYCLOBOND® I 2000 DMP

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Tramadol Enantiomers on Astec® CYCLOBOND® I 2000 DMP
Keywords: Analgesics, Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?