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  • 46123 - 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide

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46123 Sigma-Aldrich

1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide

suitable for fluorescence, ≥97.0% (TLC)

Synonym: (6-Methoxyquinolinio)acetic acid ethyl ester bromide, MQAE

  • CAS Number 162558-52-3

  • Empirical Formula (Hill Notation) C14H16BrNO3

  • Molecular Weight 326.19

  •  MDL number MFCD00467854

  •  PubChem Substance ID 329757076

  •  NACRES NA.32

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Properties

Related Categories Biochemicals and Reagents, Chelators and Ion Probes, Chelators and Ion Probes for Flow Cytometry, Chloride Probes, Detection,
Quality Level   100
assay   ≥97.0% (TLC)
mp   177-179 °C (lit.)
solubility   DMSO: soluble
  H2O: soluble
  methanol: soluble
fluorescence   λex 350 nm; λem 460 nm in 0.1 M borate pH 8.0 (quenching with Cl-)
suitability   suitable for fluorescence
storage temp.   2-8°C
SMILES string   [Br-].CCOC(=O)C[n+]1cccc2cc(OC)ccc12
InChI   1S/C14H16NO3.BrH/c1-3-18-14(16)10-15-8-4-5-11-9-12(17-2)6-7-13(11)15;/h4-9H,3,10H2,1-2H3;1H/q+1;/p-1
InChI key   DSLLHVISNOIYHR-UHFFFAOYSA-M

Description

Application

1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide, a fluorescent chloride indicator dye, may be used to measure intracellular and extracellular chloride concentrations.

Other Notes

Improved chloride probe. Used to measure chloride transport in liposome membranes

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Sensor Dyes

In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
Monika Baeumle
BioFiles 2011, 6.3, 23.
Keywords: Applications, Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Methods, Microscopy, Neurotransmission, Sol-gel, Type

Peer-Reviewed Papers
15

References

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