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48760 Sigma-Aldrich

Gentamicin sulfate from Micromonospora purpurea

~700 U/mg dried material

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Properties

Related Categories A - K, Aminoglycosides, Antibacterial, Antibiotics, Antibiotics A to Z,
biological source   Micromonospora purpurea
InChI Key   RDEIXVOBVLKYNT-HDZPSJEVSA-N
form   powder
optical activity   [α]20/D +110±8°, c = 1% in H2O
mol wt   Mr 694-723
impurities   ≤10% water
color   white to light yellow
pH   4.0-5.5 (0.1 g/mL in H2O)
solubility   H2O: 0.1 g/mL, clear, very faintly yellow
Mode of action   protein synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
  mycoplasma
storage temp.   2-8°C

Description

Application

Used as a selection agent (gentamicin-resistance gene) in molecular biology applications.

Biochem/physiol Actions

Mode of Action: Inhibits protein synthesis by binding to L6 protein of 50S ribosomal subunit.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria, and mycoplasma.

Packaging

1g, 5g, 25g

Unit Definition

1 U corresponds to 1 μg of the USP gentamicin sulfate reference standard

General description

Chemical structure: aminoglycoside

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
LY2625000
Protocols & Articles
Peer-Reviewed Papers
15

References

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