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49419 Sigma-Aldrich

L-Glutamine

BioUltra, ≥99.5% (NT)

Synonym: (S)-2,5-Diamino-5-oxopentanoic acid, L-Glutamic acid 5-amide, Levoglutamide

  • CAS Number 56-85-9

  • Linear Formula H2NCOCH2CH2CH(NH2)CO2H

  • Molecular Weight 146.14

  •  Beilstein Registry Number 1723797

  •  EC Number 200-292-1

  •  MDL number MFCD00008044

  •  eCl@ss 32160406

  •  PubChem Substance ID 57651187

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Properties

Related Categories Agave sisalana, Allium cepa (Onion), Allium sativum (Garlic), Aloe Vera, Amino Acids,
InChI Key   ZDXPYRJPNDTMRX-VKHMYHEASA-N
product line   BioUltra
assay   ≥99.5% (NT)
optical activity   [α]20/D +33.0±1°, c = 5% in 5 M HCl
impurities   insoluble matter, passes filter test
  ≤0.5% foreign amino acids
ign. residue (900 °C)   ≤0.1% (as SO4)
loss   ≤0.1% loss on drying, 110 °C
pH   5.0-6.0 (25 °C, 0.1 M in H2O)
mp   185 °C (dec.) (lit.)
solubility   H2O: 0.1 M at 20 °C, clear, colorless
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤50 mg/kg
cation traces   Al: ≤5 mg/kg
  As: ≤0.1 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
λ   0.1 M in H2O
UV absorption   λ: 260 nm Amax: 0.01
  λ: 280 nm Amax: 0.01
Gene Information   rat ... Ggt1(116568)

Description

Biochem/physiol Actions

L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

Application

L-Glutamine has been used in culture medium for hypothalamic neurons, spacer in isotachophoresis of serum proteins, growth requirement of various microorganisms.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
MA2275100

Documents

Certificate of Analysis

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
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What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Is the molecular weight of L-Glutamine 146.14 or 146.15? The label information changed.
Based on a molecular formula of C5H10N2O3, the molecular weight to seven significant figures is 146.1456. Over the years, this value may have been reported in Sigma-Aldrich documentation or on labels as either 146.15 (by rounding up) or 146.14 (by truncation). The material itself has not changed.
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Protocols & Articles

Protocols

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Peer-Reviewed Papers
15

References

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