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49449 Sigma-Aldrich

L-Glutamic acid

BioUltra, ≥99.5% (NT)

Synonym: (S)-2-Aminopentanedioic acid, Glu

  • CAS Number 56-86-0

  • Linear Formula HO2CCH2CH2CH(NH2)CO2H

  • Molecular Weight 147.13

  •  Beilstein/REAXYS Number 1723801

  •  EC Number 200-293-7

  •  MDL number MFCD00002634

  •  eCl@ss 32160406

  •  PubChem Substance ID 57651195

  •  NACRES NA.26

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Properties

Related Categories Amino Acids, BioUltra, Biochemicals and Reagents, Proteins and Amino Acids for Protein Stabilization, Proteins and Derivatives,
product line   BioUltra
assay   ≥99.5% (NT)
form   powder
optical activity   [α]20/D +31.5±1.0°, c = 5% in 5 M HCl
application(s)   cell analysis: suitable
impurities   insoluble matter, passes filter test
  ≤0.5% foreign amino acids
ign. residue   ≤0.05% (as SO4)
loss   ≤0.05% loss on drying, 20 °C (HV)
color   white
mp   205 °C (dec.) (lit.)
solubility   1 M HCl: 1 M at 20 °C, clear, colorless
density   1.54 g/cm3 at 20 °C
anion traces   chloride (Cl-): ≤100 mg/kg
  sulfate (SO42-): ≤200 mg/kg
cation traces   Al: ≤5 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤200 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  NH4+: ≤100 mg/kg
  Na: ≤200 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
λ   1 M in 1 M HCl
UV absorption   λ: 260 nm Amax: 0.1
  λ: 280 nm Amax: 0.1
storage temp.   room temp
SMILES string   N[C@@H](CCC(O)=O)C(O)=O
InChI   1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChI key   WHUUTDBJXJRKMK-VKHMYHEASA-N
Gene Information   human ... CCR2(1231), GRIA1(2890), GRIA2(2891), GRIA4(2893), GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK5(2901), GRIN2B(2904), GRM2(2912), SLC1A1(6505), SLC1A2(6506)
rat ... Gria1(50592), Grik1(29559), Grik2(54257), Grik4(24406), Grin2a(24409), Grm1(24414), Grm2(24415), Grm3(24416), Grm4(24417), Grm5(24418), Grm6(24419), Grm7(81672), Slc1a2(29482)

Description

Biochem/physiol Actions

An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).

Other Notes

Lesion-sparing agent, has excitotoxic properties; May function as precipitating agent in protein crystallization; Growth requirement of various microorganisms

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Related Content

Amino Acids Reference Charts

Amino acids are the compounds or building blocks that make up peptides and proteins. Each amino acid is structured from an amino group and a carboxyl group bound to a tetrahedral carbon. This carbon ...
Keywords: Building blocks, Gene expression, Mass spectrometry

Peer-Reviewed Papers
15

References

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