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5168 Sigma-Aldrich

Bovine Collagen

Bornstein and Traub Type V, 0.25 mg/mL

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Properties

Related Categories Attachment Factors, Cell Culture, Reagents and Supplements More...
biological source   bovine placenta
volume size   2 mL
sterility   sterile
assay   >95% (SDS-PAGE)
form   solution
packaging   vial of 0.5 mg
concentration   0.25 mg/mL
solubility   water: miscible
suitability   suitable for cell culture
shipped in   wet ice
storage temp.   2-8°C

Description

Preparation Note

The product is supplied as a sterile solution at 0.5 mg per vial at approximately 0.15 to 0.30 mg/ml in 100 mM acetic acid.

Biochem/physiol Actions

Collagen acts as a powerful marker for regeneration. Bovine collagen injections are not advisable to individuals undergoing a treatment with steroids. It is used in the deletion of telopeptide allogenic units.

General description

Collagen is a major component of several human tissues, mainly of bone. Bovine collagen is biodegradable and was first obtained from a fresh calf skin.

Type V Collagen provides structure and strength to connective tissue and is found in many places in the body, especially skin, lung, intestinal walls and walls of blood vessels. This Type V Collagen product is isolated from placenta and is purified using a multi-step process with a final purity of >95%. Type V collagen forms a triple helix composed of a Alpha 1(V)2 Alpha 2(V) heterotrimer.

Type V Collagen is typically used as a thin coating on tissue culture surfaces. This product is generally used in vitro as a substrate scaffold to enhance cell attachment, adherence and proliferation. Type V collagen may be used to culture a variety of cell types.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis


Cell Culture Guide

Milli-Q® Water Purification Solutions
Protocols & Articles

Articles

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What is the Extracellular Matrix?

The extracellular matrix (ECM) is secreted by cells and surrounds them in tissues. It has long been understood to be the structural support for cells since its characteristics set the characteristics...
Keywords: Adhesion, Cell culture, Cellular processes, Epimerizations, Growth factors, Immobilization, Sulfations

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Peer-Reviewed Papers
15

References

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