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53340 Sigma-Aldrich

L-Histidine dihydrochloride

≥99.0% (AT)

  • CAS Number 6027-02-7

  • Empirical Formula (Hill Notation) C6H9N3O2 · 2HCl

  • Molecular Weight 228.08

  •  Beilstein/REAXYS Number 6119230

  •  EC Number 227-890-5

  •  MDL number MFCD00066569

  •  PubChem Substance ID 57651406

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Properties

Related Categories Amino Acids, Biochemicals and Reagents More...
InChI Key   XEJCDBUNISUVGZ-XRIGFGBMSA-N
assay   ≥99.0% (AT)
optical activity   [α]20/D +6.5±1°, c = 8% in H2O
ign. residue   ≤0.1% (as SO4)
mp   240-245 °C (dec.)
solubility   H2O: soluble
  saline: soluble
anion traces   sulfate (SO42-): ≤50 mg/kg
cation traces   As: ≤0.1 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  NH4+: ≤500 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Zn: ≤5 mg/kg

Description

Biochem/physiol Actions

L-Histidine is a natural proteinogenic α amino acid useful as a cell growth supplement that support protein and peptide biosynthesis. L-Histidine is studied in a wide range of applications that involve imidazole chemistry and biochemisty.

L-Histidine is a positively charged imidazole-side chain containing α amino acid. It is metabolized to histamine and is a precursor of the dipeptide carnosine. As one of the 22 proteinogenic amino acids L-His is incorporated into proteins by translation processes in vitro. L-Histidine is an essential amino acid added to cell culture media.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles

Related Content

Amino Acids Reference Chart

Amino acids are the 21 standard compounds or building blocks that make up peptides and proteins, including DNA. Each amino acid is structured from an amino group and a carboxyl group bound to a tetra...
Keywords: Building blocks, Gene expression, Mass spectrometry

Peer-Reviewed Papers
15

References

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