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55156 Sigma-Aldrich

7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester

suitable for fluorescence, ≥95.0% (coupling assay to aminopropyl silica gel)

Synonym: N-Succinimidyl 7-hydroxycoumarin-3-carboxylate, Umbelliferone-3-carboxylic acid N-succinimidyl ester

  • CAS Number 134471-24-2

  • Empirical Formula (Hill Notation) C14H9NO7

  • Molecular Weight 303.22

  •  Beilstein/REAXYS Number 9419622

  •  MDL number MFCD00037568

  •  PubChem Substance ID 57651516

  •  NACRES NA.32

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Properties

Related Categories Alphabetical, Biochemicals and Reagents, Detection, Fluorescent Indicators and Probes, Fluorescent Probes, Labels, Particles and Stains,
Quality Level   100
assay   ≥95.0% (coupling assay to aminopropyl silica gel)
solubility   DMF: soluble
  DMSO: soluble
fluorescence   λex 386 nm; λem 448 nm in 0.1 M Tris pH 9.0
suitability   suitable for fluorescence
storage temp.   −20°C
SMILES string   Oc1ccc2C=C(C(=O)ON3C(=O)CCC3=O)C(=O)Oc2c1
InChI   1S/C14H9NO7/c16-8-2-1-7-5-9(13(19)21-10(7)6-8)14(20)22-15-11(17)3-4-12(15)18/h1-2,5-6,16H,3-4H2
InChI key   KFEBWCYYRFZMTJ-UHFFFAOYSA-N

Description

Application

7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester (7-OHCCA-SE) is used as a reagent to conjugate 7-Hydroxycoumarin-3-carboxylic acid (7-OHCCA) to other molecules such as amino acids via amide chemistry.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Sensor Dyes

In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
Monika Baeumle
BioFiles 2011, 6.3, 23.
Keywords: Applications, Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Methods, Microscopy, Neurotransmission, Sol-gel, Type

Peer-Reviewed Papers
15

References

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