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56968 Sigma-Aldrich

Sparfloxacin

≥99.0% (HPLC)

Synonym: 5-Amino-1-cyclohexyl-7-(cis-3,5-dimethylpiperazino)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

  • CAS Number 110871-86-8

  • Empirical Formula (Hill Notation) C19H22F2N4O3

  • Molecular Weight 392.40

  •  Beilstein/REAXYS Number 9170271

  •  MDL number MFCD00869619

  •  PubChem Substance ID 57651613

  •  NACRES NA.85

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics N-S, Biochemicals and Reagents
Quality Level   200
biological source   synthetic
assay   ≥99.0% (HPLC)
form   powder or crystals
impurities   ≤1% Total Impurities
color   yellow
Mode of action   enzyme | inhibits
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
  mycobacteria
  mycoplasma
SMILES string   C[C@H]1CN(C[C@@H](C)N1)c2c(F)c(N)c3C(=O)C(=CN(C4CC4)c3c2F)C(O)=O
InChI   1S/C19H22F2N4O3/c1-8-5-24(6-9(2)23-8)17-13(20)15(22)12-16(14(17)21)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23H,3-6,22H2,1-2H3,(H,27,28)/t8-,9+
InChI key   DZZWHBIBMUVIIW-DTORHVGOSA-N
Gene Information   human ... KCNH1(3756), TOP2A(7153)

Description

Application

Sparfoxacin is used to study antimicrobial activity against Mycobacteria and respiratory tract infections .

Biochem/physiol Actions

Sparfloxacin fluoroquinolone antibiotic that inhibits bacterial DNA gyrase (topoisomerase II) and/or topoisomerase IV. It inhibits bacterial DNA gyrase-dependent processes such as DNA polymerization, ATP-dependent-DNA supercoiling, and chromosome fragmentation.

Packaging

1g, 10g

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.Storage class (TRGS 510): Non Combustible Solids

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
RTECS 
VB1986500
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

HPLC Analysis of Antibiotics (Fluoroquinolones from Tablets) on Discovery® HS C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Antibiotics (Fluoroquinolones from Tablets) on Discovery® HS C18
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Antibiotics on Discovery® C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Antibiotics on Discovery® C18
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

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