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60178 Sigma-Aldrich

Potassium cyanide

BioUltra, ≥98.0% (AT)

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Properties

Related Categories Biochemicals and Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, R to Z,
InChI Key   YUZRZFQHUCKACF-UHFFFAOYSA-N
product line   BioUltra
assay   ≥98.0% (AT)
impurities   insoluble matter, passes filter test
pH   11.0-13.0 (25 °C, 1 M in H2O)
mp   634 °C (lit.)
solubility   H2O: 1 M at 20 °C, clear, colorless
anion traces   chloride (Cl-): ≤200 mg/kg
  sulfate (SO42-): ≤400 mg/kg
  sulfide (S2-): ≤5 mg/kg
  thiocyanate (SCN-): ≤100 mg/kg
cation traces   Al: ≤5 mg/kg
  As: ≤0.1 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤50 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤100 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  Na: ≤5000 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
λ   1 M in H2O
UV absorption   λ: 260 nm Amax: 0.06
  λ: 280 nm Amax: 0.03

Description

Application

Potassium cyanide is use to inhibit oxidative phosphorylation reactions in a wide variety of biological systems and applications.

Other Notes

Blocks electron transport to oxygen via cytochrome oxidase, hence employed in the determination of succinate dehydrogenase in submitochondrial particles by preventing substantial loss of succinate by electron flux to O2

Safety & Documentation

Safety Information

Signal word 
Danger
Target organs 
Heart, Missing Phrase - N11.00500177, Missing Phrase - N11.00500180, Testes
Supplemental Hazard Statements 
Contact with acids liberates very toxic gas.
RIDADR 
UN 1680 6.1 / PGI
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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