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61360 Sigma-Aldrich

Lactulose

≥98.0% (HPLC)

Synonym: 4-O-β-D-Galactopyranosyl-D-fructofuranose, 4-O-β-D-Galactopyranosyl-D-fructose

  • CAS Number 4618-18-2

  • Empirical Formula (Hill Notation) C12H22O11

  • Molecular Weight 342.30

  •  Beilstein/REAXYS Number 93773

  •  EC Number 225-027-7

  •  MDL number MFCD00151469

  •  PubChem Substance ID 57651848

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Disaccharide More...
InChI Key   JCQLYHFGKNRPGE-WJONTELPSA-N
assay   ≥98.0% (HPLC)
optical activity   [α]20/D −48±2°, 24 hr, c = 1% in H2O
storage temp.   room temp

Description

General description

Lactulose is a synthetic derivative of lactose. It is made up of one molecule of galactose and one molecule of fructose.

Application

Lactulose has been used in the preparation of milk.

Lactulose, a disaccharide composed of fructose and galactose units, is used as an osmolyte that relieves constipation and supports probiotic processes in the intestine and colon. Lactulose helps stabilize blood glucose and insulin levels.

Biochem/physiol Actions

Lactulose helps to decrease the concentration of blood ammonia in the treatment of hepatic encephalopathy. It is also used to treat constipation as an osmotic laxative. This non-absorbable disaccharide is catabolized through the bacterial flora to short chain fatty acids. The enzymes of the mammalian digestive tract do not have the ability to digest lactulose.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
LS6965000

Documents

Certificate of Analysis

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Protocols & Articles

Articles

Prebiotics

Prebiotic food components typically consist of polysaccharides and oligosaccharides. They can be found in milk (galactooligosaccharides or GOS) and plants with dietary fibers, and they are often prod...
BioFiles Edition 6.2
Keywords: Fermentation, Prebiotics

Peer-Reviewed Papers
15

References

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