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61962 Sigma-Aldrich

Betaine

BioUltra, ≥99.0% (NT)

Synonym: (Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine

  • CAS Number 107-43-7

  • Linear Formula (CH3)3N+CH2COO-

  • Molecular Weight 117.15

  •  Beilstein/REAXYS Number 3537113

  •  EC Number 203-490-6

  •  MDL number MFCD00012123

  •  PubChem Substance ID 57651874

  •  NACRES NA.25

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Properties

product line   BioUltra
assay   ≥99.0% (NT)
impurities   insoluble matters, passes filter test
solubility   methanol: 1 M at 20 °C, clear, colorless
anion traces   chloride (Cl-): ≤200 mg/kg
  sulfate (SO42-): ≤200 mg/kg
cation traces   Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Na: ≤100 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Zn: ≤5 mg/kg
absorption   ≤0.05 at 280 nm in methanol at 1 M
  ≤0.08 at 260 nm in methanol at 1 M
SMILES string   C[N+](C)(C)CC([O-])=O
InChI   1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
InChI key   KWIUHFFTVRNATP-UHFFFAOYSA-N

Description

Application

Betaine has been used in reverse transcription to increase the thermal stability of proteins and to destabilize the DNA helix.

Biochem/physiol Actions

Betaine has been shown to increase S-adenosylmethionine (SAM) levels and hence, may have a role in diminishing hepatic steatosis. It is an osmolyte which protects cells against environmental stress.

End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
DS5900000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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