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63559 Sigma-Aldrich

D-Mannitol

BioUltra, ≥99.0% (sum of enantiomers, HPLC)

Synonym: Mannite

  • CAS Number 69-65-8

  • Empirical Formula (Hill Notation) C6H14O6

  • Molecular Weight 182.17

  •  Beilstein/REAXYS Number 1721898

  •  EC Number 200-711-8

  •  MDL number MFCD00064287

  •  PubChem Substance ID 57651947

  •  NACRES NA.25

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Properties

Related Categories Allium cepa (Onion), BioUltra, Biochemicals and Reagents, Carbohydrates, Cell Biology,
Quality Level   200
product line   BioUltra
assay   ≥99.0% (sum of enantiomers, HPLC)
optical activity   [α]20/D +24.0±1° in borax solution acc. to Ph Eur
impurities   insoluble matter, passes filter test
  reducing sugars, complies
  ≤0.0072% free acid (as CH3COOH)
ign. residue   ≤0.01% (as SO4)
loss   ≤0.05% loss on drying, 20 °C (HV)
pH   5.0-6.5 (25 °C, 1 M in H2O)
mp   166-168 °C
  167-170 °C (lit.)
solubility   H2O: 1 M at 20 °C, clear, colorless
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤50 mg/kg
cation traces   Al: ≤5 mg/kg
  As: ≤0.1 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤1 mg/kg
  Pb: ≤1 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
λ   1 M in H2O
UV absorption   λ: 260 nm Amax: 0.04
  λ: 280 nm Amax: 0.04
SMILES string   OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI   1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
InChI key   FBPFZTCFMRRESA-KVTDHHQDSA-N

Description

Application

D-Mannitol is used as an osmolyte and transport facilitator in a variety of biological in vivo and in vitro applications, such as improvement of blood-brain barrier transport and hyperosmolar therapy. D-Mannitol is used as a substrate to identify, differentiate and characterized enzymes such as mannitol dehydrogenase(s). D-Mannitol is used in identify mannitol metabolizing bacteria.

Biochem/physiol Actions

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Other Notes

Used in discontinuous gradient centrifugation for purification of plant protoplasts. Plasmolyticum that reversibly inhibits phenylalanine ammonia-lyase activity of protoplasts at concentrations exceeding 50 mM. Component of the liquid stationary phase in the GLC separation of nitroxylene and xylenol isomers.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
RTECS 
OP2060000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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