68721 Sigma

LUCY® 506 solution



Analysis Note

Sensitivity of routine procedure is ca. 3 ng/band, with linear response between 3 and 1000 ng/band.


LUCY 506 is a fluorescent stain for protein electrophoresis, with high sensitivity and easy, fast and robust staining procedure for all kinds of SDS gels. Protein staining by LUCY 506 does not interfere with subsequent MALDI-MS.


Bottomless glass bottle. Contents are inside inserted fused cone.

Physical form

LUCY 506 is provided as a 5000× stock solution in DMF (5 mg/ml).

Legal Information

LUCY is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Precautionary statements 
UN 2265 3 / PGIII
WGK Germany 
Flash Point(F) 
136.4 °F
Flash Point(C) 
58 °C

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option:
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
Can LUCY stains be used for quantification in solution. What is the linear range?
LUCY 506 and LUCY 569 can be used to quantify proteins in solution.  They are applicable for 2 different protein concentrations (the linear range 0-50 ug/mL and 10-100 ug/mL).  Requirements are only buffer, SDS, and the LUCY dyes. Samples can be measured immediately after mixing.
Do the LUCY stains contain heavy metal?
No, the LUCY stains do not contain a heavy metal.
What are the detection limits for LUCY stains?
LUCY 506 shows highest sensitivity, with a detection limit of about 3 ng per band. The standard procedure is a post-electrophoretic stain with omission of the fixation step.
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Protocols & Articles


Introduction to PAGE

Polyacrylamide gels are formed by the reaction of acrylamide and bis-acrylamide (N,N’-methylenebisacrylamide) that results in highly cross-linked gel matrix. The gel acts as a sieve through which the...
Keywords: Buffers, Cell disruption, Electrophoresis, Gel electrophoresis, PAGE, Protein electrophoresis, Sample preparations, Separation, Western blot

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