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69453 Sigma-Aldrich

L-Homocysteine

≥98.0% (NT)

Synonym: (S)-2-Amino-4-mercaptobutyric acid

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Properties

Related Categories Amino Acids, Biochemicals and Reagents More...
InChI Key   FFFHZYDWPBMWHY-VKHMYHEASA-N
assay   ≥98.0% (NT)
optical activity   [α]/D 25.5±1.5°, c = 1 in 1 M HCl
storage temp.   −20°C

Description

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Biochem/physiol Actions

Elevated homocysteine levels in plasma and tissue are associated with brain atrophy in Alzheimer′s disease as well as in healthy eldery subjects. Increased homocysteine is due to deficiencies in vitamin B status, specifically folate, B6 and B12 vitamins, which act as cofactors for enzymes involved in homocysteine metabolism.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

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Protocols & Articles

Articles

Genotype-Phenotype-Relationships in Inborn Errors of Metabolism

More than a century has passed since Archibald Garrod connected the excretion of homogentisic acid in normal and alkaptonuric members of families with an alternative course of metabolism and entitled...
Keywords: Diagnostic, Genetic, Metabolism, Metabolites

Related Content

Amino Acids Reference Chart

Amino acids are the 21 standard compounds or building blocks that make up peptides and proteins, including DNA. Each amino acid is structured from an amino group and a carboxyl group bound to a tetra...
Keywords: Building blocks, Gene expression, Mass spectrometry

Peer-Reviewed Papers
15

References

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