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69602 Sigma-Aldrich

4-Methylumbelliferyl-β-D-glucuronide hydrate

suitable for fluorescence, ≥99.0% (HPLC)

Synonym: 4-Methylumbelliferyl-β-D-glucopyranosiduronic acid, MUG

  • CAS Number 881005-91-0

  • Empirical Formula (Hill Notation) C16H16O9 · xH2O

  • Molecular Weight 352.29 (anhydrous basis)

  •  EC Number 228-186-0

  •  MDL number MFCD09039280

  •  PubChem Substance ID 57652201

  •  NACRES NA.32

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Properties

Related Categories Alphabetical, Biochemicals and Reagents, Detection, Enzyme Substrates, Enzymes, Inhibitors, and Substrates,
Quality Level   100
assay   ≥99.0% (HPLC)
form   powder or crystals
impurities   ≤0.1% free 4-Methylumbelliferone
  ≤15% water
solubility   DMSO: 50 mg/mL, clear, colorless to very faintly yellow
fluorescence   λex 365 nm; λem 445 nm in 0.1 M phosphate pH 6.5
suitability   suitable for fluorescence
storage temp.   −20°C
SMILES string   O.CC1=CC(=O)Oc2cc(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)ccc12
InChI   1S/C16H16O9.H2O/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22;/h2-5,11-14,16,18-20H,1H3,(H,21,22);1H2/t11-,12-,13+,14-,16+;/m0./s1
InChI key   URVSQZMOFUEQAW-YYHOVTOASA-N

Description

General description

4-Methylumbelliferyl-β-D-glucuronide hydrate (MUG) is a fluorogenic substrate.

Application

4-Methylumbelliferyl-β-D-glucuronide hydrate (MUG) has been used:
• as a β-glucuronidase (GUS) substrate for fluorimetric analysis of reporter gene expression in Arabidopsis thaliana
• for the fluorimetric assay for GUS activity
• to measure liposome lysis by n-octylglucoside

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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