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71729 Sigma-Aldrich

Sodium dodecyl sulfate

≥98.0% (GC)

Synonym: Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

  • CAS Number 151-21-3

  • Linear Formula CH3(CH2)11OSO3Na

  • Molecular Weight 288.38

  •  Beilstein/REAXYS Number 3599286

  •  EC Number 205-788-1

  •  MDL number MFCD00036175

  •  eCl@ss 39093306

  •  PubChem Substance ID 57652354

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Properties

Related Categories Alkyl Sulfates, Anionic Detergents, Antigen-Vaccine Preparation, Biochemicals and Reagents, Cell Culture,
description   anionic
InChI Key   DBMJMQXJHONAFJ-UHFFFAOYSA-M
assay   ≥98.0% (GC)
mol wt   micellar avg mol wt 18,000
aggregation number   62
loss   ≤5% loss on drying
CMC   7-10 mM (20-25°C)
mp   204-207 °C (lit.)
transition temp   cloud point >100 °C
solubility   H2O: 0.1 M at 20 °C, clear, colorless
anion traces   chloride (Cl-): ≤200 mg/kg
cation traces   Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤200 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Zn: ≤5 mg/kg
HLB   40

Description

Application

Sodium dodecyl sulfate has been used in western blot lysis buffer and also to prepare SDS-loading dye.

Anionic detergent

Biochem/physiol Actions

Sodium dodecyl sulfate (SDS)/lauryl sulfate, an ionic detergent has the ability to distract biological membranes. It can block RNase and deoxyribonuclease (DNase) activity. SDS is one of the main constituents of several reagents, that are used to purify nucleic acids. It is also considered as a permeability enhancer in oral formulations.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Precautionary statements 
RIDADR 
UN1325 - class 4.1 - PG 3 - Flammable solids, organic, n.o.s., HI: all
WGK Germany 
2
RTECS 
WT1050000
Flash Point(F) 
338 °F
Flash Point(C) 
170 °C

Documents

Certificate of Analysis

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Single- & multi-channel pipettes from BRAND
Protocols & Articles
Peer-Reviewed Papers
15

References

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