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75903 Sigma-Aldrich

Guanosine

≥97.0% (HPLC)

Synonym: 9-(β-D-Ribofuranosyl)guanine, Guanine-9-β-D-ribofuranoside

  • CAS Number 118-00-3

  • Empirical Formula (Hill Notation) C10H13N5O5

  • Molecular Weight 283.24

  •  Beilstein/REAXYS Number 625911

  •  EC Number 204-227-8

  •  MDL number MFCD00010182

  •  PubChem Substance ID 329766751

  •  NACRES NA.51

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Properties

Quality Level   200
assay   ≥97.0% (HPLC)
optical activity   [α]20/D -73±2°, c = 1.5% in 1 M NaOH
impurities   ≤6.0% water
mp   250 °C (dec.) (lit.)
SMILES string   [H]O[H].NC1=Nc2c(ncn2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C(=O)N1
InChI   1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
InChI key   NYHBQMYGNKIUIF-UUOKFMHZSA-N

Description

Application

Guanosine is a purine nucleoside that upon sequential phosphoylation (kinases) forms GTP which is used by RNA polymerases to synthesis RNA(s). GTP is also important in a wide range of GTPase-dependent cell signaling processes. Guanosine is used in selective matricies such a guanosine gels (G-gels) for use in capillary electrophoresis chiral selection and other applications.

Other Notes

Currently available only in Europe.

Safety & Documentation

Safety Information

RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
WGK 3
RTECS 
MF8750000

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of Nucleosides on Ascentis® Phenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Nucleosides on Ascentis® Phenyl
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Nucleosides on Ascentis® Si (Silica)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Nucleosides on Ascentis® Si (Silica)
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Ribonucleosides on Ascentis® Si

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Ribonucleosides on Ascentis® Si
Keywords: Chromatography, High performance liquid chromatography

UHPLC/MS Analysis of 8-Hydroxy-2′-Deoxyguanosine and Related Compounds on Titan™ Silica

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of 8-Hydroxy-2′-Deoxyguanosine and Related Compounds on Titan™ Silica
Keywords: Chromatography, Mass spectrometry, Separation

Peer-Reviewed Papers
15

References

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