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81709 Sigma-Aldrich

L-Proline

BioUltra, ≥99.5% (NT)

Synonym: (S)-Pyrrolidine-2-carboxylic acid

  • CAS Number 147-85-3

  • Empirical Formula (Hill Notation) C5H9NO2

  • Molecular Weight 115.13

  •  Beilstein/REAXYS Number 80810

  •  EC Number 205-702-2

  •  MDL number MFCD00064318

  •  eCl@ss 32160406

  •  PubChem Substance ID 57652885

  •  NACRES NA.26

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Properties

Related Categories Amino Acids, Amino acids, BioUltra, Biochemicals and Reagents, Cell Biology,
Quality Level   200
product line   BioUltra
assay   ≥99.5% (NT)
form   powder or crystals
optical activity   [α]20/D −85.0±1.0°, c = 5% in H2O
application(s)   cell culture | mammalian: suitable
impurities   insoluble matter, passes filter test
  ≤0.3% foreign amino acids
ign. residue   ≤0.1%
loss   ≤0.1% loss on drying, 20 °C (HV)
color   colorless to white
pH   6.0-7.0 (25 °C, 1 M in H2O)
mp   228 °C (dec.) (lit.)
solubility   H2O: 1 M at 20 °C, clear, colorless
anion traces   chloride (Cl-): ≤100 mg/kg
  sulfate (SO42-): ≤100 mg/kg
cation traces   Al: ≤5 mg/kg
  As: ≤0.1 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  NH4+: ≤20 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
λ   1 M in H2O
UV absorption   λ: 260 nm Amax: 0.05
  λ: 280 nm Amax: 0.05
SMILES string   OC(=O)[C@@H]1CCCN1
InChI   1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
InChI key   ONIBWKKTOPOVIA-BYPYZUCNSA-N

Description

Other Notes

Protects enzymes against heat inactivation; Growth requirement of various microorganisms

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
TW3584000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

Proline Derivatives and Analogs

Proline is a non-polar proteinogenic amino acid that forms a tertiary amide when incorporated into peptides. It does not have a hydrogen on the amide group and therefore cannot act as a hydrogen bond...
Chemfiles Volume 5 Article 12
Keywords: Adhesion, Biochemistry, Catalysis, Deposition, Hydroxylations, Isomerizations, Nucleic acid hybridization, Pharmaceutical, Reductions, Substitutions, Type

Related Content

Amino Acids Reference Charts

Amino acids are the compounds or building blocks that make up peptides and proteins. Each amino acid is structured from an amino group and a carboxyl group bound to a tetrahedral carbon. This carbon ...
Keywords: Building blocks, Gene expression, Mass spectrometry

Peer-Reviewed Papers
15

References

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