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84797 Sigma-Aldrich

Poly(ethylene glycol)

BioUltra, 2,000

Synonym: PEG

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Properties

Related Categories Essential Chemicals, Materials Science, Molecular Biology, Optimization Reagents, PEG and Oligo Ethylene Glycol,
Quality Level   200
product line   BioUltra
form   powder
mol wt   Mr 1900-2200
impurities   insoluble matter:, passes filter test
  ≤0.001% peroxides (as H2O2):
pH   5.5-7.0 (25 °C, 50 mg/mL in H2O)
mp   50-53 °C
solubility   H2O: 50 mg/mL at 25 °C, clear, colorless
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤50 mg/kg
cation traces   Al: ≤5 mg/kg
  As: ≤0.1 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤200 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  Na: ≤200 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
λ   50 mg/mL in H2O
UV absorption   λ: 260 nm Amax: ≤0.1
  λ: 280 nm Amax: ≤0.04
SMILES string   C(CO)O
InChI   1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key   LYCAIKOWRPUZTN-UHFFFAOYSA-N

Description

General description

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG also interacts with cell membrane, thereby allowing cell fusion. It exhibitsstealth effect, prolonged blood circulation and excellent biocompatibility. PEG has an ability to elicit hypersensitivity reactions via stimulating complement pathway.

Application

Poly(ethylene glycol) has been used:
• as a constituent in the preparation of liquid desiccant solutions
• as a precipitating agent and additive in protein crystallization
• as a representative biocompatible polymer to decipher its interactions with cellular system at molecular level

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
TQ3500000
Flash Point(F) 
444.2 °F - closed cup
Flash Point(C) 
229.00 °C - closed cup

Documents

Certificate of Analysis (COA)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles

Articles

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of et...
Keywords: Adhesion, Bacterial conjugations, Click chemistry, Molecular biology, PEGylations, Polymerization reactions, Ring-opening polymerization

Peer-Reviewed Papers
15

References

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