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85451 Sigma-Aldrich

β-Sitosterol

≥70%

Synonym: α-Dihydrofucosterol, 22,23-Dihydrostigmasterol, 24α-Ethylcholesterol, 5-Stigmasten-3β-ol

  • CAS Number 83-46-5

  • Empirical Formula (Hill Notation) C29H50O

  • Molecular Weight 414.71

  •  Beilstein/REAXYS Number 1916165

  •  EC Number 201-480-6

  •  MDL number MFCD00003631

  •  PubChem Substance ID 329769380

  •  NACRES NA.77

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Properties

Related Categories Asymmetric Synthesis, Biochemicals and Reagents, Chemical Synthesis, Chiral Building Blocks, Complex Molecules,
biological source   plant
assay   ≥70%
form   powder
impurities   campesterol and β-sitostanol, residual
mp   136-140 °C (lit.)
functional group   hydroxyl
SMILES string   [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CC[C@@H](CC)C(C)C
InChI   1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1
InChI key   KZJWDPNRJALLNS-VJSFXXLFSA-N

Description

Application

β-Sitosterol was used to supplement diet of mice to study its effect on body mass accumulation.

Packaging

100 g in poly bottle

Biochem/physiol Actions

β-Sitosterol is a plant sterol that has hypocholesterolemic activity. Only 5% of β-Sitosterol is absorbed by humans. It is hypothesized that the cholesterol-lowering activity is by competing cholesterol for uptake by the cells or by interfering with the esterification of cholesterol. β-Sitosterol is reported to reduce the incidence of colon tumors.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
WJ2600000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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