85529 Sigma-Aldrich


BioUltra, ≥99.0% (HPLC)

Synonym: D-Glucitol

  • CAS Number 50-70-4

  • Empirical Formula (Hill Notation) C6H14O6

  • Molecular Weight 182.17

  •  Beilstein/REAXYS Number 1721899

  •  EC Number 200-061-5

  •  MDL number MFCD00004708

  •  PubChem Substance ID 57653050

  •  NACRES NA.25



Related Categories BioUltra, Biochemicals and Reagents, Biostabilization Agents, Carbohydrates, Cell Biology,
Quality Level   200
vapor density   <1 (vs air)
vapor pressure   <0.1 mmHg ( 25 °C)
product line   BioUltra
assay   ≥99.0% (HPLC)
form   powder
optical activity   [α]20/D −1.5±0.3°, c = 10% in H2O
impurities   insoluble matter, passes filter test
ign. residue   ≤0.1% (as SO4)
loss   ≤0.5% loss on drying, 20 °C (HV)
pH   5.0-7.0 (25 °C, 1 M in H2O)
mp   98-100 °C (lit.)
solubility   H2O: 1 M at 20 °C, clear, colorless
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤50 mg/kg
cation traces   Al: ≤5 mg/kg
  As: ≤0.1 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
λ   1 M in H2O
UV absorption   λ: 260 nm Amax: 0.04
  λ: 280 nm Amax: 0.045
SMILES string   OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO
InChI   1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1



Sorbitol is a sugar alcohol and slowly metabolized sweetener. Sorbitol, a bacterial culture supplement, is used for the preparation of selective plating media to culture Sorbitol-fermenting bacteria including strains of Escherichia coli and Yersinia enterocolitica.

Biochem/physiol Actions

D-Sorbitol is a sugar alcohol that is commonly used as a sugar substitute. It occurs naturally and is also produced synthetically from glucose. The food industry uses D-sorbitol as an additive in the form of a sweetener, humectant, emulsifier, thickener, or dietary supplement. D-Sorbitol has also been found in cosmetics, paper, and pharmaceuticals. Naturally, D-sorbitol occurs widely in plants via photosynthesis, ranging from algae to higher order fruits of the family Rosaceae. Allelic variation of the Tas1r3 gene affects behavioral taste responses to this sugar alcohol, suggesting that it is a T1R3 receptor ligand.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 85529.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit

A plasmolyticum that reversibly inhibits the phenylalanine ammonia-lyase activity of protoplasts at concentrations exceeding 50 mM; Synchronization of Plasmodium falciparum erythrocytic stages in culture; Increases fungal α-amylase thermostability.

Safety & Documentation

Safety Information

Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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