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90081 Sigma-Aldrich

3-O-Methylquercetin

≥97% (HPLC)

Synonym: 5,7,3′ ,4′ -Tetrahydroxy-3-methoxyflavone, Quercetin 3-O-methyl ether

  • CAS Number 1486-70-0

  • Empirical Formula (Hill Notation) C16H12O7

  • Molecular Weight 316.26

  •  Beilstein/REAXYS Number 324509

  •  MDL number MFCD00210588

  •  PubChem Substance ID 329769845

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Properties

Related Categories Cell Biology, Flavonoids, Flavonols, and Flavanols, Nutrition Research, Phytochemicals by Chemical Classification
InChI Key   WEPBGSIAWZTEJR-UHFFFAOYSA-N
assay   ≥97% (HPLC)

Description

Biochem/physiol Actions

3-O-Methylquercetin significantly inhibits cyclic adenosine monophosphate- (cAMP-) and cyclic guanosine monophosphate- (cGMP-) phosphodiesterase activity. It possess anti-inflammatory, bronchodilating properties and used in treatment of asthma. It suppresses the total inflammatory cells, tumor necrosis factor-α (TNF-α) and attenuates the production of interleukins.

3-O-Methylquercetin is a metabolite in flavone and flavonol biosynthesis. It is a naturally occurring compound present in various plants, and was shown to have potent anticancer-promoting, antioxidant, antiallergy, and antimicrobial activity, and showed strong anti-viral activity inhibition of tomato ringspot virus.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 90081.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis

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Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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