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91893 Sigma-Aldrich

Poly(ethylene glycol)

BioUltra, 400

Synonym: PEG

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Properties

Related Categories Essential Chemicals, Materials Science, Molecular Biology, Optimization Reagents, PEG and Oligo Ethylene Glycol,
Quality Level   200
product line   BioUltra
form   liquid
mol wt   Mr 380-420
impurities   insoluble matter:, passes filter test
  ≤0.02% peroxides (as H2O2):
refractive index   n20/D 1.467
pH   5.5-7.0 (25 °C, 50 mg/mL in H2O)
solubility   H2O: 50 mg/mL at 25 °C, clear, colorless
density   1.126 g/mL at 20 °C
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤50 mg/kg
cation traces   Al: ≤5 mg/kg
  As: ≤0.1 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤200 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  Na: ≤300 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
λ   50 mg/mL in H2O
UV absorption   λ: 260 nm Amax: 0.06
  λ: 280 nm Amax: 0.03
InChI   1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key   LYCAIKOWRPUZTN-UHFFFAOYSA-N

Description

General description

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It facilitates the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG also interacts with cell membrane, thereby allowing cell fusion.

Application

Poly(ethylene glycol) (PEG) has been used to dissolve JC-124, nucleotide-binding domain, leucine rich family pyrin containing 3 gene (NLRP3) inflammasome inhibitor and solubilize CoQ10, a mitochondrial coenzyme Q4.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
TQ3600000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles

Articles

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of et...
Keywords: Adhesion, Bacterial conjugations, Click chemistry, Molecular biology, PEGylations, Polymerization reactions, Ring-opening polymerization

Peer-Reviewed Papers
15

References

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