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94261 Sigma-Aldrich

LL-37 (human) trifluoroacetate salt

≥95% (HPLC)

  • Empirical Formula (Hill Notation) C205H341N61O52 · xC2HF3O2

  • Molecular Weight 4492.28 (free base basis)

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Properties

Related Categories Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antiviral,
assay   ≥95% (HPLC)
form   powder (Lyophilisate)
color   colorless to white
solubility   H2O: 1 mg/mL, clear, colorless
Mode of action   cell membrane | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
  viruses
storage temp.   −20°C

Description

Amino Acid Sequence

Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-NH2

General description

Chemical structure: peptide

Application

LL-37 is used to study host defense mechanisms.

Biochem/physiol Actions

LL-37 is a muntifunctional host defense peptide with antibacterial, antiviral, and immunomodulating activities. It is the only cathelicidin-type peptide found in human. In addition to its antimicrobial activities, LL-37 has been found to regulate inflammation and neutralize lipopolysaccharides from Gram-negative bacteria.

Packaging

1mg

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Keep in a dry place.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles
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Description

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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