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94370 Sigma-Aldrich

Uridine 5′-triphosphate trisodium salt dihydrate

≥80%

Synonym: UTP

  • CAS Number 116295-90-0

  • Linear Formula C9H12N2O15P3Na3

  • Molecular Weight 586.12

  •  Beilstein/REAXYS Number 3585234

  •  EC Number 243-347-5

  •  MDL number MFCD00150714

  •  PubChem Substance ID 57653602

  •  NACRES NA.51

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Properties

Related Categories Biochemicals and Reagents, Nucleosides, Nucleotides, Oligonucleotides, Nucleotides More...
assay   ≥80%
impurities   ≤15% UDP
  ≤5% UMP
mp   >140 °C (dec.) (lit.)
shipped in   wet ice
storage temp.   −20°C
SMILES string   [Na+].[Na+].[Na+].[H]O[H].[H]O[H].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
InChI   1S/C9H15N2O15P3.3Na.2H2O/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;;2*1H2/q;3*+1;;/p-3/t4-,6-,7-,8-;;;;;/m1...../s1
InChI key   KIYVKLDQLQZXKH-GTIFRNKBSA-K
Gene Information   human ... P2RY2(5029)
rat ... P2ry2(29597)

Description

Application

Uridine 5′-diphosphate (UDP) and Uridine 5′-triphosphate (UTP) may be used in studies on nucleic acid (RNA) biosynthesis and cell signaling. UDP is a nucleotide that upon phosphorylation to UTP becomes a substrate for enzymes such as RNA polymerase(s) and GTPases. These enzymes are involved in a wide range of applications from the synthesis of RNA to the regulation of G-coupled Protein Receptors (GPCR) and cell signaling molecules such as Rho-signaling via Guanine Nucleotide Exchange Factors (GEF).

Biochem/physiol Actions

P2Y receptor agonist.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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