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A0167 Sigma-Aldrich

Galacto-N-biose

Synonym: β-D-Gal-(1→3)-D-GalNAc, 2-Acetamido-2-deoxy-3-O-β-D-galactopyranosyl-D-galactopyranose, T Antigen

  • CAS Number 20972-29-6

  • Empirical Formula (Hill Notation) C14H25NO11

  • Molecular Weight 383.35

  •  MDL number MFCD00063995

  •  PubChem Substance ID 24890406

  •  NACRES NA.25

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Properties

Related Categories Blood Group Antigens, Glycan Component Classes, Glycobiology, Molecular Biology, O-Glycans,
Quality Level   200
assay   ≥98% (TLC)
form   powder
application(s)   thin layer chromatography (TLC): suitable
storage temp.   −20°C
SMILES string   CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O
InChI   1S/C14H25NO11/c1-4(18)15-7-12(9(20)6(3-17)24-13(7)23)26-14-11(22)10(21)8(19)5(2-16)25-14/h5-14,16-17,19-23H,2-3H2,1H3,(H,15,18)/t5-,6-,7-,8+,9+,10+,11-,12-,13-,14+/m1/s1
InChI key   HMQPEDMEOBLSQB-UFLFEMAHSA-N

Description

Application

Galacto-N-biose, a component of the galacto-N-biose/lacto-N-biose metabolic pathway, is used as a substrate to identify, differentiate and characterize enzymes such as N-acetylglucosaminyltransferase(s), fucosyl- and sialyltransferase(s), galactosidase(s) and galacto-N-biose/lacto-N-biose I phosphorylase(s) (GLNBP). Galacto-N-biose is used in lectin inhibition studies.

Substrates

A substrate for N-acetylglucosaminyltransferase, fucosyl- and sialyltransferase, and galactosidase. Also used in lectin inhibition studies.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

O-Glycans

O-Linked Neutral Glycans O-Linked Sialylated Glycans Blood Group Antigens Lewis and Cell Adhesion Glycans α-Gal-(1→3)-Gal Antigens
Glycobiology Analysis Manual, 2nd Edition
Keywords: Adhesion, Catalysis, Coagulation, Degradations, Environmental, Events, Gene expression, Glycosylations, Inflammation, Ligands, O-linked glycosylation, Phosphorylations, Sequences, Transcription, Type

Peer-Reviewed Papers
15

References

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