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A4634 Sigma-Aldrich

2-Amino-6-chloropurine riboside

≥95%

Synonym: (−)-2-Amino-6-chloropurine riboside, 6-Chloroguanine riboside

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Properties

Related Categories Asymmetric Synthesis, Biochemicals and Reagents, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks,
assay   ≥95%
form   powder
mp   165-167 °C (dec.) (lit.)
solubility   water: 10 mg/mL, clear to very slightly hazy, colorless to faintly yellow
storage temp.   −20°C
SMILES string   Nc1nc(Cl)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1
InChI   1S/C10H12ClN5O4/c11-7-4-8(15-10(12)14-7)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1
InChI key   TXWHPSZYRUHEGT-UUOKFMHZSA-N

Description

Application

2-Amino-6-chloropurine riboside is used in the biosynthesis of mutagenic and prodrug nucleosides such as 2′-deoxy-2-(p-nitrophenyl)-adenosine and 6-deoxyacyclovir and of 6-arylthio analogues.

Packaging

500 mg in poly bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Related Content

Indoles, Purines, and Their Isosteres

Substituted indoles and purines have frequently been referred to as “privileged structures” since they are capable of binding to multiple receptors with high affinity, and thus have applications acro...
Keywords: Building blocks, Medicinal chemistry

Peer-Reviewed Papers
15

References

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