EMAIL THIS PAGE TO A FRIEND
A5376 Sigma-Aldrich

Acetylsalicylic acid

≥99.0%

Synonym: 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin

  • CAS Number 50-78-2

  • Linear Formula 2-(CH3CO2)C6H4CO2H

  • Molecular Weight 180.16

  •  Beilstein/REAXYS Number 779271

  •  EC Number 200-064-1

  •  MDL number MFCD00002430

  •  PubChem Substance ID 24278218

  •  NACRES NA.21

Purchase

Properties

Related Categories A to C, Application Index, Arachidonic Acid Cascade, Biochemicals and Reagents, Cancer Research,
Quality Level   200
biological source   synthetic
assay   ≥99.0%
form   powder
color   white
pKa (25 °C)   3.5
mp   134-136 °C (lit.)
solubility   H2O: 10 mg/mL at 37 °C(lit.)
  H2O: 3 mg/mL at 25 °C(lit.)
  ethanol: 50 mg/mL
  aqueous base: decomposes
ε (extinction coefficient)   190 at 298 nm in aqueous base at 1 mM
  409 at 231 nm in aqueous base at 1 mM
  466 at 230 nm in aqueous acid at 1 mM
  68 at 278 nm in aqueous acid at 1 mM
SMILES string   CC(=O)Oc1ccccc1C(O)=O
InChI   1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
InChI key   BSYNRYMUTXBXSQ-UHFFFAOYSA-N
Gene Information   human ... ITGA2B(3674), ITGB3(3690), PTGS1(5742), PTGS2(5743)

Description

Packaging

1 kg in poly bottle

100, 250, 500 g in poly bottle

Biochem/physiol Actions

Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
VO0700000
Flash Point(F) 
482.0 °F
Flash Point(C) 
250 °C
Protocols & Articles
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?