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A5525 Sigma-Aldrich

5′-Amino-5′-deoxythymidine

  • CAS Number 25152-20-9

  • Empirical Formula (Hill Notation) C10H15N3O4

  • Molecular Weight 241.24

  •  MDL number MFCD00047488

  •  PubChem Substance ID 24890985

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Properties

Related Categories Biochemicals and Reagents, Nucleoside Analogs, Nucleosides, Nucleotides, Oligonucleotides More...
form   solid
storage temp.   2-8°C
SMILES string   CC1=CN(C2CC(O)C(CN)O2)C(=O)NC1=O
InChI   1S/C10H15N3O4/c1-5-4-13(10(16)12-9(5)15)8-2-6(14)7(3-11)17-8/h4,6-8,14H,2-3,11H2,1H3,(H,12,15,16)
InChI key   PYWLBQPICCQJFF-UHFFFAOYSA-N

Description

Application

5′-Amino-5′-deoxythymidine may be used as a substrate in the synthesis of amide-conjugated nucleosides and their analogues. 5′-Amino-5′-deoxythymidine may be used for DNA 5′-terminal site-specific modification. 5′-Amino-5′-deoxythymidine is used to produce modified thymidine dimer oligonucleotide building units (squaryl groups) to create new oligonucleotide analogues.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
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References

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