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  • A5602 - AMD3100 octahydrochloride hydrate


AMD3100 octahydrochloride hydrate

≥97% (NMR), solid

Synonym: 1,1′-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane octahydrochloride, JM3100, Plerixafor, SID791

  • CAS Number 155148-31-5 (anhydrous)

  • Empirical Formula (Hill Notation) C28H54N8 · 8HCl · xH2O

  • Molecular Weight 794.47 (anhydrous basis)

  •  PubChem Substance ID 24724394

  •  NACRES NA.77



Related Categories A-AM, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Bioactives/Supplements,
Quality Level   100
assay   ≥97% (NMR)
form   solid
storage condition   desiccated
solubility   H2O: ≥10 mg/mL, clear
originator   Sanofi Aventis
storage temp.   −20°C
SMILES string   Cl[H].Cl[H].Cl[H].Cl[H].Cl[H].Cl[H].Cl[H].Cl[H].[H]O[H].C1CNCCNCCCN(CCNC1)Cc2ccc(CN3CCCNCCNCCCNCC3)cc2
InChI   1S/C28H54N8.8ClH.H2O/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36;;;;;;;;;/h5-8,29-34H,1-4,9-26H2;8*1H;1H2



AMD3100 is a highly specific chemokine receptor CXCR4 antagonist. AMD3100 has been used in a study to determine the blockade of CXCR4 in oral squamous cell carcinoma and inhibition of lymph node metastases.


5 mg in glass bottle

Biochem/physiol Actions

AMD3100 is a highly specific chemokine receptor CXCR4 antagonist.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
What is the solubility of Product A5602, AMD3100 octahydrochloride hydrate?
AMD3100 octahydrochloride hydrate is soluble in water at 22 mg/ml.
Can solutions of Product A5602, AMD3100 octahydrochloride hydrate,be stored?
Sigma-Aldrich has not evaluated the solution stability of A5602.If no information on the solution stability is found from a literature search, we would recommend that that you prepare solutions fresh.
What biological effects has been reported for Product A5602, AMD3100 octahydrochloride hydrate?
This is a highly specific chemokine receptor CXCR4 antagonist. CXCR4 has been implicated in inflammation, cancer, and HIV infection.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
My question is not addressed here, how can I contact Technical Service for assistance?
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