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A9062 Sigma-Aldrich

Adenosine 5′-triphosphate di(tris) salt hydrate

≥95%

Synonym: 5′-ATP-DiTris

  • CAS Number 102047-34-7 (anhydrous)

  • Empirical Formula (Hill Notation) C10H16N5O13P3 · 2C4H11NO3 · xH2O

  • Molecular Weight 749.45 (anhydrous basis)

  •  eCl@ss 32160414

  •  PubChem Substance ID 24891222

  •  NACRES NA.51

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Properties

Related Categories Biochemicals and Reagents, Nucleosides, Nucleotides, Oligonucleotides, Nucleotides More...
assay   ≥95%
solubility   H2O: 50 mg/mL
cation traces   Na: ≤0.1%
shipped in   dry ice
storage temp.   −20°C
SMILES string   O.NC(CO)(CO)CO.NC(CO)(CO)CO.Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
InChI   1S/C10H16N5O13P3.2C4H11NO3.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;2*5-4(1-6,2-7)3-8;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);2*6-8H,1-3,5H2;1H2/t4-,6-,7-,10-;;;/m1.../s1
InChI key   ZMNHJZFDZFGOFE-MSQVLRTGSA-N

Description

Application

Adenosine 5′-triphosphate di(tris) salt hydrate has been used:
• to treat cells for Ca2+ influx measurements in stromal interaction molecule 1 knockout (STIM1−/−) mice and in vitro chemotaxis assay for microglial migration
• supplemented in buffer C for mitochondrial respiratory control assay and complex V activity assay
• in the inhibition of silver nano particles (AgNPs) on Na+/K+-ATPase activity

Packaging

1, 10 g in poly bottle

100 mg in poly bottle

Biochem/physiol Actions

Adenosine 5′-triphosphate di(tris) salt dehydrate is useful in applications that require the absence of metals.
Adenosine 5′-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions.

P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems

Caution

Unstable: For maximum stability, store as frozen solution at pH 3.5 to 6.8.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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