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B107 Sigma-Aldrich

L-BMAA hydrochloride

≥97% (NMR), powder

Synonym: S(+)-2-Amino-3-(methylamino)propionic acid hydrochloride

  • CAS Number 16012-55-8

  • Empirical Formula (Hill Notation) C4H10N2O2 · HCl

  • Molecular Weight 154.60

  •  MDL number MFCD00055227

  •  PubChem Substance ID 329773160

  •  NACRES NA.32

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Neurobiology, Neuroscience, Pharmacologicals,
Quality Level   100
assay   ≥97% (NMR)
form   powder
optical activity   [α]20/D +26 to +34°, c = 0.1 M in 5 M HCl(lit.)
color   white to beige
solubility   H2O: soluble (solutions may be stored for several days at 4 °C)
storage temp.   −20°C
SMILES string   Cl.CNC[C@H](N)C(O)=O
InChI   1S/C4H10N2O2.ClH/c1-6-2-3(5)4(7)8;/h3,6H,2,5H2,1H3,(H,7,8);1H/t3-;/m0./s1
InChI key   VDXYGASOGLSIDM-DFWYDOINSA-N

Description

General description

L-BMAA hydrochloride/β-N-methylamino-l-alanine (BMAA) is a cyanobacterial neurotoxin.

Application

L-BMAA hydrochloride has been used as a standard to compare all the samples in the analysis of β-N-methylamino-l-alanine (BMAA) isomers in desert crust material. It has also been used as an additive with f/2+Si medium to treat the cells of Phaeodactylum tricornutum and Thalassiosira weissflogii to study its effect on them.

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

L-BMAA hydrochloride helps to block the addition of heparan sulfate to glypican-1. It possesses unusual glutamate receptor binding properties. It may cause amyotrophic lateral sclerosis/Lou Gehrig′s disease.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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