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B3936 Sigma-Aldrich

BAY R3401

≥98% (HPLC), solid

Synonym: 4-(2-Chlorophenyl)-1-ethyl-2-methyl-5-oxo-1,4,5,7-tetrahydrofuro[3,4-b]pyridine-3-carboxylic acid isopropyl ester

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Properties

Related Categories Approved Therapeutics/Drug Candidates, B, Bayer, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
InChI Key   NPUSXSOBPNHOPH-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   solid
color   white
solubility   DMSO: 15 mg/mL
originator   Bayer
storage temp.   2-8°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

BAY R3401 is a glycogen phosphorylase inhibitor. The racemic prodrug, BAY R3401, suppresses hepatic glycogenolysis. BAY W1807, the active metabolite of BAY R3401, inhibits muscle glycogen phosphorylase a and b. It has been investigated that the metabolites of BAY R3401 suppress hepatic glycogenolysis by allosteric inhibition and dephosphorylation of phosphorylase a.

Features and Benefits

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

Light sensitive; store in amber vials.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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