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B4531 Sigma-Aldrich

Biotin disulfide N-hydroxysuccinimide ester

>98%, powder

Synonym: (2-[Biotinamido]ethylamido)-3,3′-dithiodipropionic acid N-hydroxysuccinimide ester

  • CAS Number 142439-92-7

  • Empirical Formula (Hill Notation) C22H33N5O7S3

  • Molecular Weight 575.72

  •  MDL number MFCD00466919

  •  PubChem Substance ID 24891785

  •  NACRES NA.46

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Properties

Related Categories Biotinylation, Molecular Biology, Protein Modification, Protein Structural Analysis, Proteomics,
Quality Level   200
assay   >98%
form   powder
solubility   DMF: 50 mg/mL
storage temp.   −20°C
SMILES string   [H][C@]12CS[C@@H](CCCCC(=O)NCCNC(=O)CCSSCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2
InChI   1S/C22H33N5O7S3/c28-16(4-2-1-3-15-21-14(13-35-15)25-22(33)26-21)23-9-10-24-17(29)7-11-36-37-12-8-20(32)34-27-18(30)5-6-19(27)31/h14-15,21H,1-13H2,(H,23,28)(H,24,29)(H2,25,26,33)/t14-,15-,21-/m0/s1
InChI key   LWPHUVGDBNUVHA-GXZWQRSESA-N

Description

Application

Biotinylation reagent incorporating a spacer with a cleavable disulfide linkage. Typically coupled to primary amine in the pH range 6.5-8.5. Cleavage of disulfide requires reducing agent allowing mild recovery of biotinylated compound.

Packaging

10, 100 mg in glass bottle

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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