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B6769 Sigma-Aldrich

des-Arg9-[Leu8]-Bradykinin acetate salt

≥97% (HPLC)

Synonym: Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu

  • CAS Number 115035-45-5

  • Empirical Formula (Hill Notation) C41H63N11O10

  • Molecular Weight 870.01

  •  MDL number MFCD00133250

  •  PubChem Substance ID 329773283

  •  NACRES NA.26

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Properties

Related Categories Bradykinins, Cell Biology, Cell Signaling and Neuroscience, Peptides and Proteins, Peptides for Cell Biology More...
Quality Level   200
assay   ≥97% (HPLC)
form   powder
color   white
storage temp.   −20°C
SMILES string   CC(O)=O.CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H]3CCCN3C(=O)[C@@H]4CCCN4C(=O)[C@@H](N)CCCNC(N)=N)C(O)=O
InChI   1S/C41H63N11O10.C2H4O2/c1-24(2)20-28(40(61)62)48-36(57)31-14-8-17-50(31)38(59)29(23-53)49-34(55)27(21-25-10-4-3-5-11-25)47-33(54)22-46-35(56)30-13-7-18-51(30)39(60)32-15-9-19-52(32)37(58)26(42)12-6-16-45-41(43)44;1-2(3)4/h3-5,10-11,24,26-32,53H,6-9,12-23,42H2,1-2H3,(H,46,56)(H,47,54)(H,48,57)(H,49,55)(H,61,62)(H4,43,44,45);1H3,(H,3,4)/t26-,27-,28-,29-,30-,31-,32-;/m0./s1
InChI key   XBFMNOKHQZCARQ-XXZMQFNDSA-N

Description

Amino Acid Sequence

Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu

Application

The Bradkykinin amid peptide des-Arg9-[Leu8]-Bradykinin is used as a bradykinin-1 receptor (B1R) antagonist frequently in comparison with the B1 receptor agonist des-Arg9-bradykinin.

Biochem/physiol Actions

Bradykinin receptor antagonist.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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