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B7901 Sigma-Aldrich

Boric acid

for electrophoresis, ≥99.5%

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Properties

Related Categories Biochemicals and Reagents, Biological Buffers, Buffers / Buffer salts, Buffers A to Z, Core Bioreagents,
Quality Level   200
grade   for electrophoresis
vapor pressure   2.6 mmHg ( 20 °C)
assay   ≥99.5%
form   powder
impurities   ≤0.005% Insoluble in methanol
pH   8.2-10.1
mp   160 °C (dec.) (lit.)
solubility   H2O: 40 mg/mL, clear, colorless
anion traces   chloride (Cl-): ≤0.001%
  phosphate (PO43-): ≤0.001%
  sulfate (SO42-): ≤0.01%
cation traces   Ca: ≤0.005%
  Fe: ≤0.001%
  heavy metals (as Pb): ≤0.001%
suitability   suitable for electrophoresis (as a reagent)
storage temp.   room temp
SMILES string   OB(O)O
InChI   1S/BH3O3/c2-1(3)4/h2-4H
InChI key   KGBXLFKZBHKPEV-UHFFFAOYSA-N

Description

General description

Boric acid is a weak acid and is widely used in multi-purpose solutions (MPS) as a buffering agent. It is less toxic and non-volatile in nature.

Application

Boric acid has been used as a component of tris borate buffer:
• for native polyacrylamide gel electrophoresis (PAGE) and denaturing urea-PAGE of tRNA samples(80)
• for urea-polyacrylamide electrophoresis of RNA samples(81)
• for agarose gel electrophoresis of DNA samples(82)

Packaging

1 kg in poly bottle

500 g in poly bottle

Biochem/physiol Actions

Boric acid has antibacterial and fungicidal properties. It is used in the periodontal therapy as an irrigation solution as it elicits bactericidal effects in microbial biofilms in root canal. Boric acid may favor osteoblastic activity and inhibit bone loss. It inhibits Candida albicans fungal infection and has potential to treat vaginal infection.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
ED4550000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles

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Peer-Reviewed Papers
15

References

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