• USA Home
  • B8299 - N-Butyldeoxynojirimycin

EMAIL THIS PAGE TO A FRIEND
B8299 Sigma-Aldrich

N-Butyldeoxynojirimycin

film (dried in situ)

Synonym: Miglustat, NB-DNJ

  • CAS Number 72599-27-0

  • Empirical Formula (Hill Notation) C10H21NO4

  • Molecular Weight 219.28

  •  MDL number MFCD00272581

  •  PubChem Substance ID 24892070

  •  NACRES NA.32

Purchase

Properties

Related Categories Biochemicals and Reagents, D to K, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates,
InChI Key   UQRORFVVSGFNRO-UTINFBMNSA-N
Quality Level   200
form   film (dried in situ)
Gene Information   human ... UGCG(7357)

Description

General description

N-Butyldeoxynojirimycin is an alkylated product of imino sugar deoxynojirimycin.

Application

N-Butyldeoxynojirimycin has been used:
• in the inhibition of glycolipid synthesis in neuroblastoma cells
• in the inhibition the ceramide-specific glycosyltransferase in hepatocytes
• in the inhibition of β-glucosidase (GBA2) using fluorescence- activity assay in human embryonic kidney (HEK293) cells.

Packaging

1, 5 mg in glass bottle

Biochem/physiol Actions

N-Butyldeoxynojirimycin is an inhibitor of glucosyltransferase and α-glucosidases. N-Butyldeoxynojirimycin, also known as misglustat, reduces glycolipid levels by substrate reduction therapy (SRT) and is effectively used for the treatment of glycosphingolipid lysosomal storage disorder, Gaucher disease.

α-glucosidase Inhibitor

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?