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B9934 Sigma-Aldrich

BTA-1

≥98% (HPLC), solid

Synonym: 2-(4´-Methylaminophenyl)benzothiazole

  • CAS Number 439858-28-3

  • Empirical Formula (Hill Notation) C14H12N2S

  • Molecular Weight 240.32

  •  MDL number MFCD04974146

  •  PubChem Substance ID 24724428

  •  NACRES NA.77

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Properties

Related Categories B, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology
InChI Key   FHJRKGXJBXPBGA-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   solid
color   yellow
solubility   DMSO: soluble ~10 mg/mL
storage temp.   2-8°C
Gene Information   human ... APP(351)

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

BTA-1 is a probe for β-amyloid aggregates; fluorescent thioflavin-T derivative; exhibits high affinity for amyloid deposits; displays 50-fold higher affinity than thioflavin-T; selectively stains cerebral plaques and cerebrovascular amyloid deposits in the brains of PS1/APP transgenic mice, as well as Aβ fibrils in postmortem brain tissue obtained from AD patients; crosses the blood brain barrier.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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