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C2901 Sigma-Aldrich

Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated

≥95% (HPLC), powder

Synonym: CCK-8, non-sulfated

  • CAS Number 25679-24-7

  • Empirical Formula (Hill Notation) C49H62N10O13S2

  • Molecular Weight 1063.21

  •  MDL number MFCD00076488

  •  PubChem Substance ID 24892546

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Description

Amino Acid Sequence

Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2

Application

Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated has been used in the specificity testing against gastrin and pepsinogen I proteins.

Biochem/physiol Actions

Biologically inactive form of CCK-8; CCKB/gastrin receptor agonist that has no activity at the CCKA receptor.

Cholecystokinin (CCK) is a 115 amino acid preprohormone and a neurotransmitter. It exists in many isoforms. The octapeptide of CCK (CCK-8S) is the most abundant form. CCK is mapped to human chromosome 3p22.1. CCK interacts with receptors of the gastrointestinal tract and nervous system. Polymorphisms in the CCK is implicated in hallucinations in patients with Parkinson′s disease. CCK plays a key role in the activation of the calcineurin-regulated nuclear factor of activated T-cells (NFATs).

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin


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References

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