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C3137 Sigma-Aldrich

Cholesterol

from porcine liver, Grade I, ≥98%, powder

Synonym: 3β-Hydroxy-5-cholestene, 5-Cholesten-3β-ol

  • CAS Number 57-88-5

  • Empirical Formula (Hill Notation) C27H46O

  • Molecular Weight 386.65

  •  Beilstein/REAXYS Number 1915888

  •  EC Number 200-353-2

  •  MDL number MFCD00003646

  •  PubChem Substance ID 24892335

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Properties

biological source   porcine liver
type   Grade I
assay   ≥98%
form   powder
color   white
bp   360 °C (lit.)
mp   147-149 °C (lit.)
density   1.067 g/mL at 25 °C (lit.)
SMILES string   CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI   1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
InChI key   HVYWMOMLDIMFJA-DPAQBDIFSA-N
Gene Information   human ... POLA1(5422), TOP2A(7153)
rat ... Ar(24208), Polb(29240)

Description

Biochem/physiol Actions

Major component of all biological membranes; ~25% of total brain lipid is cholesterol.

Linkage

Formerly Cat. No. CH-PL

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
FZ8400000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Cholesterol Biosynthesis

Cholesterol levels in the body come from two sources, dietary intake and biosynthesis. The majority of cholesterol utilized by healthy adults is synthesized in the liver, which produces ~70% of the t...
BioFiles 2007, 2.7, 3.
Keywords: Catalysis, Decarboxylations, Metabolic Pathways, Oxidations, PAGE, Phosphorylations, Reductions

Peer-Reviewed Papers
15

References

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