C7602 Sigma


from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%

Synonym: (R,R)-3,3′-Dithiobis(2-aminopropionicacid)

  • CAS Number 56-89-3

  • Linear Formula [-SCH2CH(NH2)CO2H]2

  • Molecular Weight 240.30

  •  Beilstein Registry Number 1728094

  •  EC Number 200-296-3

  •  MDL number MFCD00064228

  •  eCl@ss 32160406

  •  PubChem Substance ID 24892973



Related Categories Amino Acids, Amino Acids & Derivatives, Amino Acids & Vitamins, Amino Acids and Vitamins, Amino acids,
biological source   non-animal source
assay   98.5-101.0%
form   powder
impurities   endotoxin, tested
mp   >240 °C (dec.) (lit.)
solubility   1 M HCl: 100 mg/mL
suitability   meets EP testing specifications
  suitable for cell culture



1 kg in poly bottle

10 mg in glass bottle

25, 100 g in poly bottle


L-Cystine has been used as a supplement in astroglial-conditioned media to culture cerebral astroglia. It has been used in several techniques, such as HPLC-FD, UHPLC-UV, UHPLC-MS, and triple quadrupole tandem mass spectrometry (UHPLC-MS/MS), to differentiate BMAA (β-N-methylamino-L-alanine), the cyanobacterial neurotoxin, from other diamino acids.
L-Cystine has been used as a supplement in oocyte culture media to improve oocyte maturation and parthenogenesis of embryonic development.

Biochem/physiol Actions

Cystinuria is characterized with renal transport and excretion of L-Cystine. Cysteine is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Cysteine is a source of disulfide linkage in protein and is associated with sulfur transport. At physiological pH, cysteine undergoes rapid oxidation to form cystine. Reduced availability of cysteine or cystine, influences leukocyte metabolism. L-Cystine is necessary for oxygen production and LDL (low density lipoprotein) modification by arterial smooth muscle cells.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C7602.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 

Cell Culture Guide

Stabilizer Protein and RNA Stabilization Reagents
Protocols & Articles


MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

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Peer-Reviewed Papers


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