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C7866 Sigma-Aldrich

CGP-53353

solid

Synonym: 5,6-Bis[(4-fluorophenyl)amino]-2H-isoindole-1,3-dione, DAPH 2

  • CAS Number 145915-60-2

  • Empirical Formula (Hill Notation) C20H13F2N3O2

  • Molecular Weight 365.33

  •  MDL number MFCD00938569

  •  PubChem Substance ID 24892990

  •  NACRES NA.77

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Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

Selective PKCβII inhibitor. IC50 - 410 nM for PKCβII vs 3.8 μM for PKCβI. Inhibits nPKCs and aPKCs only above 22 μM and other kinases such as protein kinase A, casein kinase I and II, c-src kinase, c-lyn kinase, c-fgr kinase, and v-abl kinase at an IC50 of greater than 50 μM.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
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