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C8276 Sigma-Aldrich

6-Chloropurine riboside

Synonym: 6-Chloropurine-9-β-D-ribofuranoside

  • CAS Number 5399-87-1

  • Empirical Formula (Hill Notation) C10H11ClN4O4

  • Molecular Weight 286.67

  •  Beilstein/REAXYS Number 40573

  •  EC Number 226-438-4

  •  MDL number MFCD00005738

  •  PubChem Substance ID 24893040

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Properties

Related Categories Biochemicals and Reagents, Nucleoside Analogs, Nucleosides, Nucleotides, Oligonucleotides More...
InChI Key   XHRJGHCQQPETRH-KQYNXXCUSA-N
mp   158-162 °C (dec.) (lit.)
storage temp.   −20°C

Description

Application

6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. 6-Chloropurine riboside, especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles
Peer-Reviewed Papers
15

References

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