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C9357 Sigma-Aldrich

Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl)

≥96% (HPLC)

Synonym: XJ735

  • CAS Number 153381-95-4

  • Empirical Formula (Hill Notation) C23H32N8O7

  • Molecular Weight 532.55

  •  MDL number MFCD11046000

  •  PubChem Substance ID 329775202

  •  NACRES NA.26

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Other Peptides, Peptides and Proteins, Peptides for Cell Biology More...
Quality Level   200
assay   ≥96% (HPLC)
storage temp.   −20°C
SMILES string   C[C@@H]1NC(=O)c2cccc(CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O)c2
InChI   1S/C23H32N8O7/c1-12-19(35)31-15(6-3-7-26-23(24)25)21(37)28-11-17(32)30-16(9-18(33)34)22(38)27-10-13-4-2-5-14(8-13)20(36)29-12/h2,4-5,8,12,15-16H,3,6-7,9-11H2,1H3,(H,27,38)(H,28,37)(H,29,36)(H,30,32)(H,31,35)(H,33,34)(H4,24,25,26)/t12-,15-,16-/m0/s1
InChI key   HRASXYOWQQTBAQ-RCBQFDQVSA-N
Gene Information   human ... NPY(4852)

Description

Amino Acid Sequence

Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl

Biochem/physiol Actions

Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) (XJ735) is an RGD containing cyclic peptide (peptidomimetic) used as an antagonist specific to integrin αvβ3. XJ735 is used to study the role of integrin αvβ3 in cell-matrix interactions and processes.

Antagonist of RGD peptidomimetic αVβ3 integrin containing both anionic and cationic binding sites that straddle the RGD binding domain.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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