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D1071 Sigma-Aldrich

Decoyinine

Synonym: 9-(6-Deoxy-D-β-erythro-hex-5-en-2-ulofuranosyl)adenine

  • CAS Number 2004-04-8

  • Empirical Formula (Hill Notation) C11H13N5O4

  • Molecular Weight 279.25

  •  PubChem Substance ID 329798669

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics by Mechanism of Action, Biochemicals and Reagents, Inhibits an Enzyme,
InChI Key   UZSSGAOAYPICBZ-SOCHQFKDSA-N
form   solid
Mode of action   enzyme | inhibits
antibiotic activity spectrum   Gram-positive bacteria
storage temp.   2-8°C

Description

Application

Decoyinine is used to study the inhibition of cell wall synthesis, to inhibit RNA synthesis, to lower intracellular GTP levels in Streptococcus mutans, and to initiate sporulation in Bacillus.

Biochem/physiol Actions

Decoyinine is a Xanthosine monophosphate (XMP) aminase inhibitor and GMP synthetase inhibitor.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Nucleotide Synthesis in Cancer Cells

Neoplastic cells are highly dependent on the de novo synthesis of nucleotides to maintain sufficient pools to support DNA replication and the production of RNA. The metabolic pathways supporting nucl...
Keywords: Biofiles, Cancer, Catalysis, Citric Acid Cycle, DNA replication, Gene expression, Glycolysis, Metabolic Pathways, Metabolism, Metabolites, Nucleotide Synthesis, PAGE, Pentose phosphate pathway, Pyrimidine synthesis, Support

Peer-Reviewed Papers
15

References

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